Italian Registry on telemedicine in community pharmacies, with the aim of ensuring disease screening and continuity of care for patients served by pharmacies authorized to provide this service.

• Omboni S, Khan NA, Kunadian V, Olszanecka A, Schutte AE, Mihailidou AS. Sex Differences in Ambulatory Blood Pressure Levels and Subtypes in a Large Italian Community Cohort. Hypertension. July 2023;80(7):1417-1426. Https://doi.org/10.1161/HYPERTENSIONAHA.122.20589
• Lundwall K, Kahan T, Omboni S. Blood pressure in atrial fibrillation and in sinus rhythm during ambulatory blood pressure monitoring: data from the TEMPLAR project. Hypertens Res. Oct. 23, 2023. Https://doi.org/10.1038/s41440-023-01473-x
• Omboni S, Ballatore T, Rizzi F, Tomassini F, Campolo L, Panzeri E. Age-related patterns of ambulatory blood pressure in a large cohort of individuals referred to Italian community pharmacies: results from the TEMPLAR project. J Hypertens. Feb. 1, 2023;41(2):336-343. Https://doi.org/10.1097/HJH.0000000000003337
• Omboni S, Ballatore T, Rizzi F, Tomassini F, Campolo L, Panzeri E, Lundwall K, Kahan T. 24-hour ambulatory blood pressure telemonitoring in patients at risk of atrial fibrillation: results from the TEMPLAR project. Hypertens Res. September 2022;45(9):1486-1495. Https://doi.org/10.1038/s41440-022-00932-1
• Omboni S, Campolo L, Panzeri E. Telehealth in chronic disease management and the role of the Internet of Medical Things: the Tholomeus® experience. Expert Rev Med Devices. July 2020;17(7):659-670. Https://doi.org/10.1080/17434440.2020.1782734
• Omboni S, Mancinelli A, Rizzi F, Parati G. Telemonitoring of 24-Hour Blood Pressure in Local Pharmacies and Blood Pressure Control in the Community: The TEMPLAR Project. Am J Hypertens. June 11, 2019;32(7):629-639. Https://doi.org/10.1093/ajh/hpz049
• Omboni S, Ballatore T, Rizzi F, Tomassini F, Campolo L, Panzeri E. Feasibility of 24-hour blood pressure telemonitoring in community pharmacies: the TEMPLAR project. J Hypertens. Oct. 1, 2021;39(10):2075-2081. Https://doi.org/10.1097/HJH.0000000000002895
• Omboni S, Ballatore T, Rizzi F, Tomassini F, Panzeri E, Campolo L. Telehealth at scale can improve chronic disease management in the community during a pandemic: An experience during the COVID-19 pandemic. PLoS One. September 29, 2021;16(9):e0258015. Https://doi.org/10.1371/journal.pone.0258015

International Registry on Outpatient Monitoring of Arterial Stiffness, with the aim of evaluating the usefulness of this technique in the management of patients with hypertension.

• Omboni S, Alfie J, Arystan A, Avolio A, Barin E, Bokusheva J, Bulanova N, Butlin M, Cuffaro P, Derevyanchenko M, Grigoricheva E, Gurevich A, Konradi A, Muiesan ML, Paini A, Pereira T, Statsenko ME, Tan I; VASOTENS Registry Study Group. Association of 24-hour central hemodynamics and stiffness with cardiovascular events and all-cause mortality. The VASOTENS Registry. J Hypertens. September 1, 2024;42(9):1590-1597. Https://doi.org/10.1097/HJH.0000000000003763
• Omboni S, Posokhov I, Parati G, Arystan A, Tan I, Barkan V, Bulanova N, Derevyanchenko M, Grigoricheva E, Minyukhina I, Mulè G, Orlova I, Paini A, Peixoto Maldonado JM, Pereira T, Ramos-Becerra CG, Tilea I, Waisman G. Variable association of 24-hour peripheral and central hemodynamics and stiffness with hypertension-mediated organ damage: the VASOTENS Registry. J Hypertens. April 2020;38(4):701-715. Https://doi.org/10.1097/HJH.0000000000002312
• Omboni S, Posokhov I, Parati G, Rogoza A, Kotovskaya Y, Arystan A, Avolio A, Barkan V, Bulanova N, Cardona Muñoz E, Grigoricheva E, Konradi A, Minyukhina I, Muiesan ML, Mulè G, Orlova I, Pereira T, Peixoto Maldonado JM, Statsenko ME, Tilea I, Waisman G. Web-based telemonitoring of ambulatory blood pressure and arterial stiffness in patients at cardiovascular risk. First results of the VASOTENS (Vascular health ASsessment Of The hypertENSive patients) Registry. J Clin Hypertens (Greenwich). Aug 2019;21(8):1155-1168. Https://doi.org/10.1111/jch.13623
• Omboni S, Posokhov I, Parati G, Rogoza A, Kotovskaya Y, Arystan A, Avolio A, Barkan V, Bulanova N, Cardona Muñoz E, Grigoricheva E, Konradi A, Minyukhina I, Muiesan ML, Mulè G, Orlova I, Pereira T, Peixoto Maldonado JM, Statsenko ME, Tilea I, Waisman G. Vascular Health Assessment of Hypertensive Patients (VASOTENS) Registry: Study Protocol of an International, Web-Based Telemonitoring Registry for Ambulatory Blood Pressure and Arterial Stiffness. JMIR Res Protoc. June 29, 2016;5(2):e137. Https://doi.org/10.2196/resprot.5619
• Omboni S, Arystan A, Benczur B. Ambulatory monitoring of central arterial pressure, wave reflections, and arterial stiffness in patients at cardiovascular risk. J Hum Hypertens. Apr 2022;36(4):352-363. Https://doi.org/10.1038/s41371-021-00606-4
• Omboni S, Posokhov IN, Kotovskaya YV, Protogerou AD, Blacher J. Twenty-Four-Hour Ambulatory Pulse Wave Analysis in Hypertension Management: Current Evidence and Perspectives. Curr Hypertens Rep. Oct 2016;18(10):72. Https://doi.org/10.1007/s11906-016-0681-2
• Omboni S, Posokhov IN, Rogoza AN. Relationships between 24-hour blood pressure variability and 24-hour central arterial pressure, pulse wave velocity, and augmentation index in hypertensive patients. Hypertens Res. 2017 Apr;40(4):385-391. Https://doi.org/10.1038/hr.2016.156
• Omboni S, Posokhov IN, Rogoza AN. Evaluation of 24-Hour Arterial Stiffness Indices and Central Hemodynamics in Healthy Normotensive Subjects versus Treated or Untreated Hypertensive Patients: A Feasibility Study. Int J Hypertens. 2015;2015:601812. Https://doi.org/10.1155/2015/601812

International Registry of Ambulatory Blood Pressure and Arterial Hypertension.

• Omboni S, Aristizabal D, De la Sierra A, Dolan E, Head G, Kahan T, Kantola I, Kario K, Kawecka-Jaszcz K, Malan L, Narkiewicz K, Octavio JA, Ohkubo T, Palatini P, Siègelovà J, Silva E, Stergiou G, Zhang Y, Mancia G, Parati G. Hypertension types defined by clinic and ambulatory blood pressure in 14,143 patients referred to hypertension clinics worldwide. Data from the ARTEMIS study. J Hypertens. Nov. 2016;34(11):2187–98. Https://doi.org/10.1097/HJH.0000000000001074
• Hoshide S, Kario K, de la Sierra A, Bilo G, Schillaci G, Banegas JR, Gorostidi M, Segura J, Lombardi C, Omboni S, Ruilope L, Mancia G, Parati G. Ethnic differences in the degree of morning blood pressure surge and in its determinants between Japanese and European hypertensive subjects: data from the ARTEMIS study. Hypertension. Oct. 2015;66(4):750-6. Https://doi.org/10.1161/HYPERTENSIONAHA.115.05958

Literature reviews that form the basis of the Tholomeus® project or that refer to or cite publications based on studies conducted using Tholomeus®.

• Bit-Avragim N, Bousquet J, Cantù S, Omboni S, Ravot E, Tunnah P. The evolving reality of digital health. Digit Health. September 26, 2024;10:20552076241277646. Https://doi.org/10.1177/20552076241277646
• Omboni S. Telemedicine for hypertension management: a paradigm shift from telemonitoring to digital therapeutics. Expert Rev Med Devices. July–December 2023;20(9):711–714. Https://doi.org/10.1080/17434440.2023.2242270
• Omboni S, Padwal RS, Alessa T, Benczúr B, Green BB, Hubbard I, Kario K, Khan NA, Konradi A, Logan AG, Lu Y, Mars M, McManus RJ, Melville S, Neumann CL, Parati G, Renna NF, Ryvlin P, Saner H, Schutte AE, Wang J. The worldwide impact of telemedicine during COVID-19: current evidence and recommendations for the future. Connect Health. Jan. 4, 2022;1:7–35. Https://doi.org/10.20517/ch.2021.03
• Omboni S, Panzeri E, Campolo L. E-Health in Hypertension Management: An Insight into the Current and Future Role of Blood Pressure Telemonitoring. Curr Hypertens Rep. June 6, 2020;22(6):42. https://doi.org/10.1007/s11906-020-01056-y
• Omboni S. Telemedicine During the COVID-19 Pandemic in Italy: A Missed Opportunity? Telemed J E Health. Aug 2020;26(8):973-975. Https://doi.org/10.1089/tmj.2020.0106
• Omboni S. Connected Health in Hypertension Management. Front Cardiovasc Med. June 13, 2019;6:76. Https://doi.org/10.3389/fcvm.2019.00076
• Omboni S. Pharmacist-led hypertension management combined with blood pressure telemonitoring in a primary care setting may be cost-effective in high-risk patients. J Clin Hypertens (Greenwich). February 2019;21(2):169-172. Https://doi.org/10.1111/jch.13467
• Omboni S, Tenti M. Telepharmacy for the management of cardiovascular patients in the community. Trends Cardiovasc Med. February 2019;29(2):109-117. Https://doi.org/10.1016/j.tcm.2018.07.002
• Omboni S, Caserini M. Effectiveness of pharmacist intervention in the management of cardiovascular diseases. Open Heart. Jan. 3, 2018;5(1):e000687. Https://doi.org/10.1136/openhrt-2017-000687
• Omboni S, Caserini M, Coronetti C. Telemedicine and M-Health in Hypertension Management: Technologies, Applications, and Clinical Evidence. High Blood Press Cardiovasc Prev. September 2016;23(3):187-96. Https://doi.org/10.1007/s40292-016-0143-6
• Omboni S, Ferrari R. The role of telemedicine in hypertension management: focus on blood pressure telemonitoring. Curr Hypertens Rep. 2015 Apr;17(4):535. Https://doi.org/10.1007/s11906-015-0535-3
• Omboni S, Sala E. The pharmacist and the management of arterial hypertension: the role of blood pressure monitoring and telemonitoring. Expert Rev Cardiovasc Ther. 2015 Feb;13(2):209-21. Https://doi.org/10.1586/14779072.2015.1001368
• Omboni S, Gazzola T, Carabelli G, Parati G. Clinical usefulness and cost-effectiveness of home blood pressure telemonitoring: a meta-analysis of randomized controlled trials. J Hypertens. March 2013;31(3):455-67; discussion 467-8. Https://doi.org/10.1097/HJH.0b013e32835ca8dd

• Omboni S, Guarda A. Impact of home blood pressure telemonitoring on blood pressure control: a meta-analysis of randomized controlled trials. Am J Hypertens. 2011 Sep;24(9):989-98. Https://doi.org/10.1038/ajh.2011.100

Guidelines that form the basis of the Tholomeus® project or that cite publications based on studies conducted using Tholomeus®.

• Omboni S, McManus RJ, Bosworth HB, Chappell LC, Green BB, Kario K, Logan AG, Magid DJ, McKinstry B, Margolis KL, Parati G, Wakefield BJ. Evidence and Recommendations on the Use of Telemedicine for the Management of Arterial Hypertension: An International Expert Position Paper. Hypertension. November 2020;76(5):1368-1383. Https://doi.org/10.1161/HYPERTENSIONAHA.120.15873
• Omboni S, Bilo G, Saladini F, Di Guardo A, Palatini P, Parati G, Pucci G, Virdis A, Muiesan ML. Standards for the Implementation, Analysis, Interpretation, and Reporting of 24-Hour Ambulatory Blood Pressure Monitoring: Recommendations of the Italian Society of Hypertension. High Blood Press Cardiovasc Prev. September 2024;31(5):425-436. Https://doi.org/10.1007/s40292-024-00670-0
• Stergiou GS, Parati G, Kollias A, Schutte AE, Asayama K, Asmar R, Bilo G, de la Sierra A, Dolan E, Filipovsky J, Head G, Kario K, Kyriakoulis KG, Mancia G, Manios E, Menti A, McManus RJ, Mihailidou AS, Muntner P, Niiranen T, Ohkubo T, Omboni S, Protogerou A, Saladini F, Sharman J, Shennan A, Shimbo D, Topouchian J, Wang J, O’Brien E, Palatini P. Requirements for the design and function of blood pressure measuring devices used for the management of hypertension: Consensus Statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability and STRIDE BP. J Hypertens. Dec. 1, 2023;41(12):2088-2094. Https://doi.org/10.1097/HJH.0000000000003482
• Khan NA, Stergiou GS, Omboni S, Kario K, Renna N, Chapman N, McManus RJ, Williams B, Parati G, Konradi A, Islam SM, Itoh H, Mooi CS, Green BB, Cho MC, Tomaszewski M. Virtual management of hypertension: lessons from the COVID-19 pandemic—International Society of Hypertension position paper endorsed by the World Hypertension League and the European Society of Hypertension. J Hypertens. Aug. 1, 2022;40(8):1435-1448. Https://doi.org/10.1097/HJH.0000000000003205
• Parati G, Stergiou GS, Bilo G, Kollias A, Pengo M, Ochoa JE, Agarwal R, Asayama K, Asmar R, Burnier M, De La Sierra A, Giannattasio C, Gosse P, Head G, Hoshide S, Imai Y, Kario K, Li Y, Manios E, Mant J, McManus RJ, Mengden T, Mihailidou AS, Muntner P, Myers M, Niiranen T, Ntineri A, O’Brien E, Octavio JA, Ohkubo T, Omboni S, Padfield P, Palatini P, Pellegrini D, Postel-Vinay N, Ramirez AJ, Sharman JE, Shennan A, Silva E, Topouchian J, Torlasco C, Wang JG, Weber MA, Whelton PK, White WB, Mancia G; Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension. Home blood pressure monitoring: methodology, clinical relevance, and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension. J Hypertens. September 1, 2021;39(9):1742-1767. Https://doi.org/10.1097/HJH.0000000000002922
• Omboni S, Palatini P, Parati G; Working Group on Blood Pressure Monitoring of the Italian Society of Hypertension. Standards for clinical reporting of ambulatory blood pressure monitoring in daily practice: recommendations from the Italian Society of Hypertension. *Blood Press Monit.* Oct. 2015;20(5):241-4. Https://doi.org/10.1097/MBP.0000000000000135